Clinical Trials | FORE Research
biotech FORE Research Program

Clinical Trials

FORE and Florida Orthopaedic Institute partner with industry leaders to conduct rigorous clinical trials across orthopaedic subspecialties, advancing care through evidence-based research and real-world outcomes data.

FDA-regulated studies
·
IRB-approved protocols
·
Multi-center collaborations
4
Subspecialties
12+
Active Trials
6
Follow-up Studies
20+
Industry Partners

Active Enrolling Trials

Analgesic Requirement for Post-Operative Pain Control in Elective 1–3 Level TLIF or Lumbar Laminectomy

Comparison of Thoracolumbar Interfacial Plane Block with Exparel to Bupivacaine HCL. Evaluating optimal post-operative pain management strategies following lumbar spine surgery.

Prospective, Observational Spine Fusion Registry for Ossdsign Bone Graft Substitutes

Real-world clinical practice registry tracking outcomes of Ossdsign bone graft substitutes in spine fusion procedures, contributing to evidence-based treatment protocols.

Safety and Effectiveness of the Hip Innovation Technology Reverse Hip Replacement System (AHH-Lyons Site)

A pivotal study evaluating the safety and effectiveness of the HIT Reverse Hip Replacement System in primary total hip arthroplasty patients.

Safety and Effectiveness of the Hip Innovation Technology Reverse Hip Replacement System (TGH-Miranda Site)

Parallel pivotal study at the TGH site evaluating HIT Reverse Hip Replacement System outcomes in primary total hip arthroplasty.

Multicenter Postmarket Surveillance Study: Canary Canturio™ TE Tibial Extension

Postmarket surveillance study monitoring real-world safety and performance of the Canary Canturio TE Tibial Extension system across multiple centers.

Augmented Reality Versus Conventional Jig Controls in Total Knee Arthroplasty for Osteoarthritis (ARVIS)

A prospective study comparing augmented reality-guided alignment with conventional jig-based controls in TKA, assessing accuracy and clinical outcomes.

Persona OsseoTi Keel Compatibility Study

Evaluating the compatibility and performance of the Persona OsseoTi Keel tibial implant system in total knee arthroplasty.

BioBrace Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears

A prospective, single-blind, multicenter, randomized controlled pivotal study evaluating the safety and effectiveness of the BioBrace Implant during arthroscopic rotator cuff repair.

Post Market Confirmatory Study: Integrity Implant System for Rotator Cuff Tear Augmentation

Interventional post-market confirmatory study assessing the Integrity Implant System's clinical performance in rotator cuff tear augmentation procedures.

MACI Multicenter Clinical Outcomes Registry

Multicenter registry tracking real-world clinical outcomes for Matrix-Induced Autologous Chondrocyte Implantation (MACI), a cartilage restoration procedure for the knee.

Revive

An active enrolling shoulder study. Details available upon inquiry.

AMR Stemless Reverse vs. SMR Reverse Shoulder System (Lima): Comparative RSA Study

A randomized, multicenter, prospective study comparing safety and efficacy outcomes of total reverse shoulder arthroplasty using AMR Stemless Reverse versus the SMR Reverse Shoulder System.

Active Follow-up Studies

Enrollment complete. Ongoing patient follow-up and data collection.

3 Spine RWE

A real-world evidence study tracking outcomes across three spine procedures, contributing patient-reported and clinical data to a growing evidence base.

Compass Observational Registry: aprevo™ Spine Surgery

Clinical Outcome Measures in Personalized aprevo™ Spine Surgery. A registry capturing patient outcomes in personalized interbody devices for spinal fusion.

Medtronic PLF

A study tracking posterolateral fusion outcomes using Medtronic instrumentation and biologics, assessing fusion rates and patient-reported functional improvement.

Assessment of P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion with Instrumentation

Evaluating P-15L synthetic bone graft as a biologic scaffold in TLIF procedures, with outcomes data informing future spinal fusion strategies.

Age as a Risk Factor for Poor Outcomes of Bridge-Enhanced ACL Restoration (BEAR®)

A prospective cohort clinical trial evaluating how patient age influences clinical outcomes following Bridge-Enhanced ACL Restoration, a biologic alternative to traditional ACL reconstruction.

High-Intensity Home Stretching vs. Physical Therapy for Adhesive Capsulitis

Prospective, randomized controlled trial assessing the efficacy of a high-intensity home stretching device compared to traditional physical therapy in the non-operative management of frozen shoulder.

Biomechanical Comparison of Fixation Constructs for Thumb CMC Dislocation: Devin's Technique Versus K‑Wires Versus Suture Anchor–Tape Constructs (5th CMC)

The Divergent Role of Body Mass Index Across Four Common Hand Operations: A Comparative Systematic Review of Carpal Tunnel, Cubital Tunnel, Trigger Finger, and Dupuytren's Contracture Surgery

Impact of Obesity on Complications and Outcomes After Cubital Tunnel Release: A Systematic Review

Impact of Obesity on Complications and Outcomes After Dupuytren's Contracture Surgery: A Systematic Review

Impact of Obesity on Complications and Outcomes After Trigger Finger Release: A Systematic Review

Occult Amyloid Deposition Identified During Reconstruction of Chronic Lunate Dislocation Presenting as Progressive Median Neuropathy: A Case Report

Generation Z Wrist Fractures: Retrospective Review of Patients 18–35 Who Underwent Distal Radius ORIF

Generation Z Wrist Fractures: Case Series Who Underwent Distal Radius ORIF

Development of DRUJ OA After TWA

Second Metacarpal Cortical Index as a Predictor of Periprosthetic Radiolucency After Total Wrist Arthroplasty

Patient Burden on CMC Arthroplasty

Patient Burden of Delay in Post-Operative Rehabilitation for Proximal Zone 5 to 7 Extensor Tendon Repairs: Single-Center Retrospective Cohort Study

The Impact of Occupational Therapy on Patient Outcomes Following Total Wrist Arthroplasty

Nerve Repair With Allograft 7cm or 10cm

Retrospective Review: HA+ Nerve Wrap in Revision Carpal Tunnel Release Versus Revision Cubital Tunnel Release

Retrospective Review: Pronator Release with CTR and Without CTR

Retrospective Review: Revision Carpal Tunnel Release at a Single Institution

Retrospective Review: HA+ in Revision CTR vs. Revision CUBTR

Surgical Fixation of Scaphoid Fractures Using Plates and Locking Screws: Technique and Outcomes

Insufficient Rehabilitation After Flexor Tendon Repair: Impact on Patient Outcomes and Costs in a Single-Center Retrospective Cohort

Proximal Phalanx Injection vs. Conventional Injection Technique for Trigger Finger

Volar Locking Plates with Screw Fixation Versus Headless Compression Screws for Surgical Fixation of Scaphoid Fractures: A Noninferiority Analysis

Retrospective Review: Distal Radius Fracture Fixation with Dorsal Compression Reduction Technique Versus Standard Technique

CMC Touch Prosthesis Technique Paper

Primary Cubital Tunnel Release With Guardrail Bumper

Three Digit Proximal Phalanx Fracture Fixation: A Case Report

Prospective Patient Perceptions of EMG/NCS Studies

Effectiveness of Cannabidiol vs. Narcotics for Post-Operative Pain Control in Elective Shoulder Arthroscopic Surgery

Nerve Protection Evaluation: Cubital Tunnel Syndrome Decompression (COVERED) Axoguard HA+ Nerve Protector

Disappearance of Scratch Collapse Phenomena Post-Operatively

Partner With FORE on a Clinical Trial

FORE and Florida Orthopaedic Institute offer industry partners access to a high-volume, multi-subspecialty orthopaedic practice with experienced investigators and a dedicated research team.

Contact Our Research Team